DC2 – Effect of external fields on the induction of nucleation

This project aims at studying the effect of an external field on biomolecules nucleation by applying an electric field or a laser pulse (NPLIN) into a microfluidic set-up. Globular proteins will be studied. Specific objectives:

1-Develop a microfluidic platform for triggering biomolecule crystallisation using an external field: electric field and/or laser pulse.

2-Measure statistical data on biomolecule nucleation and provide statistical data to the community.

3-Comparison of results obtained with electric field and/or a laser pulse with those obtained with ultrasounds or magnetic fields.

4-Modelling the effect of an external field on nucleation of biomolecule.

CINaM, CNRS, France


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