To develop a technical process strategy decision methodology and assess energy consumption and environmental impact of the developed processes and compare against conventional industrial practise. Specific objectives:
1-Identify key process parameters that affect biomolecules crystallisation kinetics and crystals’ properties.
2- Develop life-cycle assessment (LCA) methods. Initial effort will be based on available information from literature, SANOFI R&D/SECOYA and market research. Further details will be provided by the DN researchers. The holistic analysis, from solvent and crystalliser design to full scale process operation, provides reliable prediction regarding the overall feasibility.
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