This project aims to achieve a comprehensive understanding of how electrical protocols can be designed to control the chemical and thermal environments during the crystallisation process. Specific objectives:
1-Understand the mechanisms by which ohmic heating influence protein solubility, nucleation and crystal development using well characterised protein systems of biological or structural importance.
2-Evaluate the impact of electrochemical reactions and the presence of metal impurities during crystallisation. 3-Modelling crystallisation kinetics process (e.g. nucleation time) supported by ex situ and in-situ monitoring methods.
UMINHO, Portugal
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